Recent discussions online have highlighted potential associations between Ozempic and hair loss. Alongside other reported side effects like “Ozempic face” and “Ozempic butt,” this connection has been difficult to confirm until now.
A new study has established a link between semaglutide (the generic name for Ozempic and Wegovy) and hair loss, revealing that the issue might be more pronounced in women. It’s essential to note that this research is preliminary and has not yet undergone peer review, which is a vital part of the scientific process.
These findings raise important questions about whether using semaglutide can contribute to hair loss and, more importantly, what can be done to counteract this effect. Here’s an overview of the study’s conclusions and insights from medical professionals.
What Did the Study Discover?
The investigation, which was published on the pre-print server medRxiv, examined data from over 1,900 individuals prescribed semaglutide, comparing them to a group of 1,300 patients treated with the older weight loss medication bupropion-naltrexone (Contrave). To clarify, semaglutide belongs to the glucagon-like peptide-1 (GLP-1) receptor agonists category, working within the body to slow down food movement through the gut and signaling the brain to reduce hunger. This mechanism often leads to lower food intake and prolonged feelings of fullness.
The researchers specifically concentrated on individuals taking Wegovy, which is FDA-approved for obesity treatment. Although Ozempic is also FDA-approved, it is primarily intended for blood sugar management in those with type 2 diabetes.
By analyzing medical records, the researchers found that those on semaglutide had a 50% increased likelihood of being diagnosed with hair loss issues, with the risk being twice as high for women compared to men. While the study suggests that further research is necessary, it raises valid concerns for anyone considering or already taking these medications.
Why Could Semaglutide Induce Hair Loss?
It’s important to clarify that the study didn’t conclude that semaglutide causes hair loss directly; rather, it identified a correlation. However, many doctors believe that semaglutide could indeed contribute to hair loss.
Dr. Mir Ali, medical director of the MemorialCare Surgical Weight Loss Center, explains, “We often observe hair loss in patients who experience substantial weight loss through various methods, including medications, diet, exercise, or surgery. Hair loss can be linked to weight loss, particularly rapid weight reduction.”
Hair growth follows specific cycles, and factors such as rapid weight loss or severe stress can disrupt these cycles, increasing the risk of hair loss. Dr. Ife J. Rodney, founding director of Eternal Dermatology + Aesthetics, adds that quick weight loss can shift hair from the growth phase (anagen) to the resting and shedding phase (telogen), potentially leading to conditions like telogen effluvium, which results in significant hair shedding.
Medical professionals are not surprised by these findings. Dr. Gary Goldenberg from Mount Sinai Hospital notes that he has witnessed this effect with all GLP-1 medications.
As individuals using semaglutide typically consume less food, they may be at risk of nutritional deficiencies, particularly in iron, zinc, and protein—nutrients essential for hair health. With possible side effects like nausea and vomiting, those taking these medications may be ingesting even fewer nutrients than needed, weakening hair follicles and leading to thinning and shedding.
Semaglutide might also affect hormone levels, including cortisol, which can indirectly impact the health of hair follicles, particularly in women whose hair may be more sensitive to hormonal fluctuations.
How to Prevent and Address Hair Loss Associated with Semaglutide
If you’re considering or currently taking semaglutide, it’s crucial to know that hair loss isn’t a guaranteed outcome. However, there is a risk involved.
While nothing can eliminate the risk entirely, ensuring adequate protein intake can be beneficial, according to Dr. Ali. He also recommends taking any dietary supplements as advised by your healthcare provider. Dr. Goldenberg emphasizes monitoring your iron and zinc levels as well. It’s worth consulting with your doctor before beginning any supplement regimen.
While it may be tempting to try biotin supplements, Dr. Rodney advises that this approach is unlikely to be effective because the issue isn’t due to a deficiency in biotin. Instead, opting for a well-rounded supplement might yield better results.
Incorporating a balanced diet rich in fruits and vegetables can further decrease the chances of nutritional deficiencies that could elevate hair loss risk. If you find yourself experiencing hair loss while on semaglutide and it’s concerning, Dr. Rodney suggests considering topical treatments like minoxidil, typically used for pattern baldness, but effective for temporary hair loss as well.
If you feel overwhelmed by managing hair loss, consulting a dermatologist may be beneficial. Dr. Goldenberg points out that numerous regenerative treatments are now available that can help reverse or improve hair loss related to semaglutide.
Keep in mind that any hair loss attributed to semaglutide is unlikely to be permanent. According to Dr. Ali, “Once weight stabilizes, hair typically returns to its previous state.”
